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Interventions to cultivate physician empathy: a systematic review

BMC Medical Educationvolume 14, Article number: 219 (2014) | Download Citation

Abstract

Background

Physician empathy is both theoretically and empirically critical to patient health, but research indicates that empathy declines throughout medical school and is lower than ideal among physicians. In this paper, we synthesize the published literature regarding interventions that were quantitatively evaluated to detect changes in empathy among medical students, residents, fellows and physicians.

Methods

We systematically searched PubMed, EMBASE, Web of Science and PsychINFO in June of 2014 to identify articles that quantitatively assessed changes in empathy due to interventions among medical students, residents, fellows and physicians.

Results

Of the 1,415 articles identified, 64 met inclusion criteria. We qualitatively synthesized the findings of qualified studies by extracting data for ten study metrics: 1) source population, 2) sample size, 3) control group, 4) random assignment, 5) intervention type, 6) intervention duration, 7) assessment strategy, 8) type of outcome measure, 9) outcome assessment time frame, and 10) whether a statistically significant increase in empathy was reported. Overall, the 64 included studies were characterized by relatively poor research designs, insufficient reporting of intervention procedures, low incidence of patient-report empathy assessment measures, and inadequate evaluations of long-term efficacy. 8 of 10 studies with highly rigorous designs, however, found that targeted interventions did increase empathy.

Conclusions

Physician empathy appears to be an important aspect of patient and physician well-being. Although the current empathy intervention literature is limited by a variety of methodological weaknesses, a sample of high-quality study designs provides initial support for the notion that physician empathy can be enhanced through interventions. Future research should strive to increase the sample of high-quality designs through more randomized, controlled studies with valid measures, explicit reporting of intervention strategies and procedures, and long-term efficacy assessments.

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Background

In their Learning Objectives for Medical School Education, the Association of American Medical Colleges states that, “physicians must be compassionate and empathetic in caring for patients” [1]. Similarly, the American Medical Association’s first principle of medical ethics asserts the following: “A physician shall be dedicated to providing competent medical care, with compassion and respect for human dignity and rights” [2]. These statements illustrate that the field of medicine is not only committed to producing and upholding the most knowledgeable and skillful physicians possible, but also the most caring and empathic. Within the field of medicine, there is disagreement regarding the precise definition of empathy [3, 4]. Some researchers define physician empathy as a “cognitive attribute that involves an ability to understand the patient’s inner experiences and perspective and a capability to communicate this understanding” [3]. Others describe four components of the empathy construct: 1) emotive, the ability to imagine and share a patient’s psychological state or feelings; 2) moral, the physician’s internal motivation to express empathy; 3) cognitive, the intellectual ability to identify and understand a patient’s perspectives and emotions; and 4) behavioral, the ability to communicate this understanding of the patient’s perspectives and emotions [5]. Most constructions of empathy have in common, however, an understanding of the emotional states of others and expression of this understanding.

While there is some disagreement regarding the exact components of empathy, there is wide consensus that physician empathy significantly affects patients in a variety of ways. Physician empathy has been associated with higher levels of patient satisfaction [6–12], adherence to medical recommendations or regimens [10, 13–16], and improved clinical outcomes [6, 16–20]. Moreover, empathy appears to positively influence physicians themselves, as empathy has been linked to lower burnout [21], higher well-being [21–23], higher ratings of clinical competence [3], and less medical-legal risk [24–26]. Physician empathy may even reduce health care costs, as patient centered communication styles have been associated with lower diagnostic test expenditures [27].

Despite considerable evidence demonstrating the benefits of physician empathy for patients and physicians, empathy is at a lower than ideal level in medicine. Studies indicate that physicians often overlook or miss empathic opportunities during patient encounters [28–32], and tend to spend significantly more time and energy on biomedical inquiry and offering medical explanations to patients [8, 32]. In one study, physicians acknowledged or explored empathic opportunities only 10% of the time [32]. Patient reports also point to a shortage of physician empathy [33]. Yet, not only is there a shortage of empathy among medical students and physicians, numerous studies show that empathy declines throughout medical training, in both medical school and residency [34–39]. As trainees experience an increase in personal distress from burnout, higher rates of depression and decreased quality of life during their training, they are less likely to experience or demonstrate empathy. This distress is potentially promoted by deficiencies in several aspects of the medical curricula, including the formal (e.g. lack of formal empathy training), informal (e.g. inadequate mentors, shorter hospital stays, and inappropriate learning environments), and hidden (e.g. mistreatment of students and high workload) medical curricula [38].

The lack of empathy among physicians and the decline in empathy throughout medical training offer reasons for concern, especially given the relationship between physician empathy and patient health and well-being [6–20]. It is incumbent upon medical educators, and the field in general, to investigate methods to enhance medical student and physician empathy. Although studies have reviewed and examined interventions to increase empathy among medical students [40] and in health and human services [41], no review has been done on the full body of literature regarding interventions designed to quantitatively detect changes in medical student or physician empathy. Thus, the present study seeks to systematically review and synthesize the existing literature of quantitatively evaluated interventions aimed at cultivating empathy among medical students, residents, fellows, and attending physicians.

Methods

In June of 2014, we conducted a systematic review of the literature, searching the online databases PubMed, EMBASE, Web of Science, and PsychINFO (Figure 1). We collaborated with a librarian from the Biomedical Library at the University of Pennsylvania to discuss and refine our search strategy.

Figure 1
figure1

Study flow diagram. Illustration of database search process to identify studies that met inclusion criteria.

Full size image

In PubMed, we used the following search terms as key words: (1) empathy or caring or compassion, (2) medical students or physicians, (3) medical education or clinical competence or training or workshop, and (4) communication. This search generated 574 articles. In EMBASE, the following search terms were used as descriptors: (1) empathy, (2) medical student or resident or physician, (3) medical education, (4) clinical competence, and (5) doctor patient relation or interpersonal communication. This search produced 359 articles. In Web of Science, we searched using the following key terms: (1) empathy, (2) medical students or physicians, and (3) education or training or workshop or intervention. This search generated 550 articles. Finally, in PsychINFO, we used the following descriptors: (1) empathy, (2) medical students or physicians, and (3) medical education or training. The PsychINFO search produced 145 articles.

Overall, our initial literature search generated 1,628 citations. Elimination of duplicate articles produced 1,400 citations, and an additional 15 articles were identified through references. In turn, 1,415 articles were screened by title and abstract. Of these, 1,303 articles were excluded from further review, including correlational studies, theoretical papers, articles that failed to assess empathy, and publications with non-medical populations. The full texts of the remaining 112 studies were retrieved and assessed for eligibility using the inclusion criteria outlined below, yielding 64 eligible studies.

Our inclusion criteria specified that each study: 1) elucidate that some type of intervention was used, 2) explicitly state that “empathy” was being evaluated or measured, 3) assess changes in empathy by reporting quantitative outcomes using statistical methods, and 4) examine empathy in medical students, residents, fellows or physicians. We considered only articles written in the English language. After reviewing the titles and abstracts of all articles retrieved through our initial database search, we obtained full texts of potentially eligible studies. We also reviewed the reference sections of these selected articles to obtain any additional studies not found through our initial database search.

Members of the research team (ZK, JW) independently examined the full texts of studies that passed title and abstract review and met inclusion criteria. Each article was assessed for a variety of metrics, including source population, sample size, type of intervention, duration of intervention, assessment strategy, type of outcome measure, and outcome assessment time frame. Data were extracted and finalized through discussion among the research team.

The review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (see Additional file 1).

Results

We identified 64 studies [42–105] that quantitatively assessed empathy interventions in our specified population (see Additional file 2). 50 of these 64 studies were published within the past ten years. We reviewed the findings from these articles by extracting data for ten major study metrics: 1) the study source population, 2) the study sample size, 3) the presence or absence of a control group, 4) whether or not random assignment was used, 5) the type of intervention, 6) the duration of the intervention, 7) the empathy assessment strategy, 8) the type of outcome measure, 9) the outcome assessment time frame post-intervention, and 10) whether or not a statistically significant increase in empathy was reported. This summary method allowed the research team to investigate similarities and differences among articles and to attain a more general appreciation for the strengths and weaknesses of the current literature regarding empathy interventions. Thus, the results are presented and organized around the ten metrics used to evaluate each study.

  1. 1)

    Source population

    The source population assessment was divided into four major categories: medical students, residents, fellows and physicians. Of the 64 studies reviewed, 36 (56%) evaluated empathy interventions with medical students, 13 (20%) with residents, 2 (3%) with fellows, and 15 (23%) with attending physicians. In addition, six studies evaluated empathy in a “mixed” population, including three articles assessing both medical students and residents, two assessing residents and fellows, and one article assessing medical students and attending physicians.

  2. 2)

    Sample size

    Sample sizes ranged from 11 participants to 439 participants. The mean sample size was approximately 89 participants, with a median of 78, Q1 of 28, Q3 of 125, and a standard deviation of 75. 21 studies (33%) exhibited sample sizes of 100 or more participants, while 24 studies (38%) reported sample sizes of fewer than 50 participants.

  3. 3)

    Control group

    Of the 64 studies reviewed, 35 (55%) used a control or comparison group.

  4. 4)

    Random assignment

    Of the 35 controlled interventions, 24 (69%) used random assignment.

  5. 5)

    Intervention type

    A variety of intervention types were utilized. 20 studies (31%) employed “communication skills training” interventions. We classified an intervention as “communication skills training” if the study authors explicitly referred to their intervention as a communication skills training or workshop. Often, communication skills training interventions were comprised of a variety of features, including didactic sessions on effective communication and empathy, experiential learning, and skills or behavior-based workshops. For instance, Winefield and Chur-Hansen [103] used both didactic material (i.e., lecture, videotape and handouts) and training workshops in which medical students practiced their communications skills by interviewing standardized patients and receiving feedback. Tulsky et al. [99] used an audiotape CD-Rom training program that allowed physicians to observe the demonstration of an effective communication skill and review or reflect upon their own conversations and implementation of the skill.

    Seven studies (11%) primarily used a “role playing” intervention, typically involving experiential learning in which study participants acted as a patient or family member. For example, Chunharas et al. [51] sought to build medical student empathy for patients receiving intramuscular or subcutaneous injection by asking medical students to take turns injecting each other with saline solution.

    Six studies (9%) utilized some form of the “humanities,” including reflective writing, a literature course, and theater. For instance, Shapiro et al. [93] used a reflective writing intervention, in which medical students wrote essays from the point of view of either hypothetical or standardized patients.

    In addition, two articles reported an intervention involving “motivational interviewing training,” a counseling approach aimed at patient behavior change. Three interventions used “balint training,” which entails small group discussions focused on patient emotions. Two studies emphasized mindfulness-based stress reduction (MBSR), a type of meditation characterized by nonjudgmental, moment-to-moment awareness. One intervention used problem-based learning sessions that focused on empathy and communication.

    Finally, 23 studies (35%) were categorized as “other.” Those studies classified as “other” could not be logically organized into a more general category. Studies classified as “other” often used a variety of intervention types. For instance, Krasner et al. [69] constructed an intervention that involved MBSR and the humanities, particularly reflective writing, appreciative inquiry exercises, and other educational and experiential tasks. Riess et al. [82] created an empathy training protocol that included education in the neurobiology and physiology of empathy, real-time biofeedback during physician-patient encounters, and mindfulness exercises. In addition, many of the “other” type interventions exhibited similarities to “communication skills training” interventions, as various didactic, experiential or skills-based elements were utilized.

  6. 6)

    Duration of intervention

    Duration of empathy interventions (i.e., amount of time spent on intervention activities) ranged from 40 minutes to approximately 96 hours, with a mean of 15 hours, median 12 hours, Q1 of 4 hours, Q3 of 18 hours, and a standard deviation of 74.4 hours. Interventions occurred over the course of days, weeks, months, and even years. 19 studies (30%) were regarded as “not explicit” (N/E) in their reporting of intervention duration, particularly the number of intervention hours.

  7. 7)

    Assessment strategy

    Empathy assessment strategies were evaluated using two major categories: timing of the empathy assessment (pre- versus post-intervention) and overall study design evaluation (within-group versus between-group). 58 (91%) of the 64 studies assessed empathy both pre- and post-intervention. 15 studies (23%) used between-group comparison to evaluate empathy changes, 32 studies (50%) used within-group comparison methods, and 17 (27%) utilized both a within- and between-group assessment strategy.

  8. 8)

    Outcome measures

    Among the outcome measures used to assess changes in empathy, 31 studies (48%) used self-report measures. 33 (52%) employed other-report measures where others (including patients) evaluated their perception of a medical practitioner’s empathy. Only six studies (9%) evaluated changes in empathy using patient reports. Four assessed empathy using more than one type of outcome measure.

    Self-report measures involved a self-report survey or single question. A variety of self-report survey types were used, including the Jefferson Scale of Physician Empathy (JSPE), Empathic Tendency Scale (ETS), Empathic Skill Scale (ESS), Balanced Emotional Empathy Scale (BEES), Empathy Construct Rating Scale (ECRS), and Interpersonal Reactivity Index (IRI). The JSPE was the most commonly used self-report survey, appearing in 15 of the 31 studies employing self-report measures.

    Other-report outcome measures varied as well. Typically, these measures involved assessments of participant behaviors during clinical encounters or medical interviews by trained observers. For instance, Bonvicini et al. [46] used trained observers and an empathy coding system to evaluate physician empathy during audiotaped recordings of physician-patient interactions. 24 of the 32 articles employing other-report measures evaluated empathy during real or staged patient encounters. Six studies assessed empathy based on medical students’ or residents’ written responses to hypothetical patient scenarios, and two studies used tests requiring decoding of emotional facial expressions.

  9. 9)

    Outcome assessment time frame

    Outcome assessment time frames ranged from immediately following the intervention to 21 years post-intervention. We defined immediately following the intervention as studies that measured empathy within a day after the end of an intervention. 30 studies (47%) assessed empathy immediately following the intervention. 17 studies (27%) evaluated empathy at some time after immediate assessment. Of these studies, seven (11%) assessed empathy 1–4 weeks post-intervention, ten (15%) assessed empathy 1–6 months post-intervention, three evaluated 12 months post-intervention, one study assessed after 3 years, and one study assessed empathy between four and 21 years post-intervention. Nine studies evaluated empathy at multiple time points post-intervention. 20 studies (31%) were not explicit (N/E) about the outcome assessment time frame.

  10. 10)

    Significant increase in empathy reported

    42 (66%) of the 64 reviewed studies reported a statistically significant increase in empathy. 14 studies (22%) showed no significant change in empathy. Finally, eight studies (12%) were classified as “mixed” because they reported some measure with no significant change in empathy and another measure with a significant increase in empathy. Cahan et al. [49] reported the results of two distinct pilot studies. Pilot 1 was a between-group study design that showed no significant result. Pilot 2 used a within-group study design that resulted in a significant increase in empathy. Both Chunharas et al. [51] and Norfolk et al. [76] reported a significant increase in empathy within groups, but no increase resulted from between-group comparison. Riess et al. [81] reported a significant increase in empathy on the Consultation and Relational Empathy (CARE) measure, but no change on the Balanced Emotional Empathy Scale (BEES), Jefferson Scale of Physician Empathy (JSPE), and Ekman Facial Decoding Test. Riess et al. [82] found a significant increase in empathy on the CARE measure, the Neurobiology and Physiology of Empathy Test and the Ekman Facial Decoding test, but no significant increase on the BEES and JSPE. Sanson-Fisher & Poole [87] reported no significant change in empathy when evaluated within the intervention group, but a significant increase resulted from between-group comparison. Shapiro et al. [92] found an increase in empathy on the BEES, but no change on the Empathy Construct Rating Scale (ECRS). Finally, Shapiro et al. [93] used a study-specific thematic coding system for writing samples of medical students and found an increase in empathy for physicians, but no change in empathy for the family or patient.

Study design quality assessment

Given that two thirds of included studies reported a significant increase in empathy (not including mixed results), we performed a qualitative assessment of study design quality (see Additional file 3). Study design quality was based on three metrics: 1) presence or absence of a control group, 2) whether or not random assignment was used, and 3) the reliability and validity of the outcome measure. Further, outcome measures were categorized into three types: 1) reliable and valid outcome measure (+), 2) reliable, but not valid outcome measure (+/−), and 3) neither reliable, nor valid outcome measure (−). If reliability or validity information was not available in published material, efforts were made to contact the authors to obtain this information.

The three quality metrics were used to establish a study design rating system composed of three tiers. 10 studies (16%) were classified as Tier 1. Tier 1 studies were the most rigorous, involving randomized, controlled interventions, along with reliable and valid outcome measures (+). 9 studies (14%) were categorized as Tier 2. Tier 2 studies were composed of one of two quality metric arrangements: 1) randomized, controlled interventions, along with reliable, but not valid outcome measures (+/−), or 2) controlled interventions devoid of random assignment, along with reliable and valid outcome measures (+). Finally, 45 studies (70%) were classified as Tier 3: all other study designs.

We compared study design quality to our significant increase in empathy metric (Figure 2, Additional file 3). Of the ten studies classified as Tier 1, eight reported a significant increase in empathy, and two showed mixed results. Of the nine studies classified as Tier 2, six (66%) showed a significant increase in empthy and three (33%) exhibited no change in empathy. Of the 45 studies classified as Tier 3, 28 (62%) reported a significant increase in empathy, six (13%) showed mixed results, and eleven (24%) reported no change in empathy. Compared to the 80% of studies showing a significant increase in empathy in Tier 1, 63% (34/54) of studies in Tier 2 and Tier 3 reported a significant increase in empathy. Moreover, all 14 studies that reported no significant change in empathy were categorized into either Tier 2 or Tier 3.

Figure 2
figure2

Comparison of study design quality with significant increases in empathy. Number of studies exhibiting significant, non-significant and mixed effects among Tiers 1, 2 and 3.

Full size image

Characteristics of tier 1 studies

Tier 1 studies were heterogeneous in their source populations: 50% involved medical students and 50% involved residents, fellows, or physicians, suggesting that empathy interventions may be effective during or after training. A variety of intervention types were used in Tier 1 studies: 30% had been classified as “communication skills training,” 40% were categorized as “other,” and “role playing,” “motivational interviewing,” and “humanities” interventions were each represented by a single study. Tier 1 studies also exhibited a relatively balanced array of outcome measure types, as 60% used other-report measures, 50% employed self-report measures, and 30% used patient-report measures. Furthermore, 50% of Tier 1 studies evaluated empathy 1–6 months post-intervention. Five Tier 1 studies reported effect size data; however, no two of those five used the same methodology to calculate effect size, leaving us unable to make meaningful comparisons based on those data.

Discussion

The present study provides a novel synthesis and analysis of empathy interventions in medicine. Previous studies have systematically reviewed empathy measures and their relationship to patient outcomes in cancer care [106], emotion skills training for medical students [107], and empirical research on empathy in medical students and physicians [108]. This study, however, has systematically reviewed and synthesized interventions that quantitatively evaluate changes in empathy among medical students, residents, fellows, and physicians.

This review has generated a number of key findings. As previously mentioned, 66% of studies reported a significant increase in empathy. While this result was encouraging, we sought to further evaluate this trend by assessment of study design. Results of this assessment indicated that although the majority of studies (84%) lacked highly rigorous study designs (Tier 2 and Tier 3), all ten studies classified as Tier 1 exhibited either significant increases in empathy or mixed effects. Moreover, 80% of Tier 1 studies showed a significant increase in empathy (not mixed), while only 63% of studies in Tier 2 and Tier 3 reported significant increases. Despite the small number of studies, these findings generally support the hypothesis that intervention can increase empathy among physicians and medical students, not only because of the high incidence of significant increases in empathy in Tier 1, but also because Tier 1 studies included balanced assortments of other study metrics (e.g., study population, intervention type, outcome measure type, and outcome assessment time frame). Taken together, the Tier 1 results suggest that empathy can be enhanced through a variety of intervention types targeted toward medical students, residents, fellows and physicians, and that increased empathy may persist beyond the immediate post-intervention period.

Although these findings are encouraging, it is important to highlight the fact that only ten studies were classified as Tier 1. Further, only half of the Tier 1 studies explicitly reported effect sizes. These findings add uncertainty to our inferences about the cultivation of empathy among medical students and physicians, and also point to major limitations associated with the full body of physician empathy intervention literature: significant fractions of eligible studies lacked rigorous study designs, lacked control groups, and failed to use random assignment. Well-controlled and randomized studies are the most reliable way to account for, or minimize, potential confounding factors, and the fact that they are rare in the physician empathy intervention literature should be taken into account when examining the high incidence of significant outcomes. The overall literature was also marked by relatively small sample sizes and vague reporting of intervention durations and outcome-assessment time frames. While empathy interventions were classified into different categories, the literature was characterized by a wide array of intervention types that typically showed both similar and disparate underlying features. In some cases, articles lacked detailed descriptions of the intervention. If the ultimate goal is implementation of effective empathy-increasing interventions, the literature does not enable other institutions to replicate these outcomes.

Outcome assessment time frames, and particularly the high prevalence of studies only assessing empathy immediately following the intervention, should also be highlighted as a weakness of the current literature. While medical student or physician empathy may significantly increase immediately after an intervention, there is limited insight available about long-term efficacy. Just over a quarter of studies explicitly reported follow-up quantitative evaluations of empathy at some time (i.e., 1 week to 21 years) after an immediate assessment of the intervention.

The majority of empathy interventions were targeted toward medical students. Although this trend is not surprising given that medical school has an explicit curriculum, including communication skills training in a growing number of institutions, researchers and educators should be wary of the fact that these empathic skills degrade over time [34–39]. Therefore, interventions aimed at enhancing empathy among residents, fellows and physicians may be more important to ensure that patients consistently receive empathic care from their physicians. Little is known about the long-term efficacy of empathy interventions. Even if medical student empathy is enhanced through interventions, a lack of long-term efficacy could have serious consequences for arguably the most critical population – practicing physicians and their patients.

Another limitation of the literature involved outcome measure type. Empathy was measured in a variety of ways, but the vast majority of studies used self-report or other-report measures, and only six employed patient reports to measure physician empathy. Indeed, close to half of the reviewed studies used self-report measures to evaluate changes in empathy. Some of these self-report surveys are psychometrically reliable and validated, yet little is known about the relationship between self-report measures of empathy and behavioral or patient-report measures. It is also the case that measurements of empathy in a medical population may be subject to significant social desirability bias; therefore, particularly with self-report measures of empathy, it can be difficult to say whether interventions increase empathy, or awareness of the desirability of an empathetic physician. Self-report surveys can be an effective and reliable measure of physician empathy, but they must be validated against behavioral or patient-report measures.

A recent study indicated that a commonly used self-report measure, the Jefferson Scale of Physician Empathy (JSPE) [109–111], exhibited statistically significant correlations with a patient-report measure, the Jefferson Scale of Patient Perceptions of Physician Empathy (JSPPPE) [112]. The strongest correlations have been demonstrated with real patients [113], although weaker correlations exist with standardized patients as well [112]. Further, a systematic review concluded that physician empathy is associated with beneficial outcomes based on patient-report measures in cancer care. However, little is known about the relationship between the reliable and valid patient-report measures examined in the cancer care study and physician self-report empathy measures like the JSPE [106]. In other words, there may be a misalignment between the outcome measure type (patient-report) most prevalent in studies investigating the association between physician empathy and patient outcomes, and an outcome measure type common to empathy interventions (self-report). It is worth noting that while only six studies overall used patient-report measures, three of these studies were categorized as Tier 1. Further, all three of these Tier 1 studies employed reliable and valid patient-report measures that have been associated with beneficial patient outcomes. These results may add confidence to the inference that targeted interventions may not only increase empathy, but also lead to beneficial effects for patients.

In addition to the weaknesses of the current empathy intervention literature, our study may have been marked by a number of limitations, such as that imposed by the availability of information in the published materials (e.g., intervention durations, procedures, outcome assessment time frames, and reliability and validity of measures). Our efforts to contact authors to obtain further information yielded mixed results. Our study may have also been limited by a ‘publication bias’, which could relate to the high incidence of studies reporting significant effects. Thus, the literature may contain a disproportionately small number of null results.

Overall, results of the study design quality assessment suggest that empathy can be enhanced in our study population. However, given the relatively small number of Tier 1 studies and limitations of the full body of literature, we suggest strategies to facilitate progress within empathy interventions for medical students, residents, fellows, and physicians: 1) Further determining the correlation between self-report, other-report (behavioral), and patient-report measures of physician empathy to ensure future studies are able to utilize reliable and validated measures that have an established connection between change in self-report and increase in patient perception of empathy; 2) Establishing consensus about which measurement types should be used to evaluate physician empathy so that smaller studies may be aggregated in the future in a meta-analysis; 3) Ensuring adequate and explicit reporting of intervention procedures and implementation to promote transparent and easily replicable studies; 4) Conducting more high-quality randomized controlled study designs to establish a larger sample of Tier 1 studies, and thereby evaluating their efficacy with a higher degree of confidence because confounding factors have been controlled for; 5) Given the degradation of empathy, recognizing the need to develop and test interventions at multiple time points in training and practice of medicine; and 6) Lengthening outcome assessment time frames to investigate the long-term efficacy of empathy interventions.

Conclusions

Although considerably more research must be undertaken, the present study provides valuable insight into the current state of the empathy intervention literature and suggests that targeted interventions may be able to cultivate physician empathy. The reported shortage of empathy and decline in empathy during medical training only amplifies the importance of finding reliable interventions for physicians and physicians-in-training. Indeed, heightened empathy among medical practitioners could not only lead to a more ethical healthcare system, but also to enhanced health and well-being for patients and practitioners themselves.

References

  1. 1.

    Association of American Medical Colleges (AAMC): Learning Objectives for Medical Student Education: Guidelines for Medical Schools. [https://members.aamc.org/eweb/upload/Learning%20Objectives%20for%20Medical%20Student%20Educ%20Report%20I.pdf]

  2. 2.

    American Medical Association (AMA): Principles of Medical Ethics. [http://www.ama-assn.org/ama/pub/physician-resources/medical-ethics/code-medical-ethics/principles-medical-ethics.page?]

  3. 3.

    Hojat M, Gonnella JS, Mangione S, Nasca TJ, Veloski JJ, Erdmann JB, Callahan CA, Magee M: Empathy in medical students as related to academic performance, clinical competence and gender. Med Educ. 2002, 36: 522-527. 10.1046/j.1365-2923.2002.01234.x.

  4. 4.

    Hemmerdinger JM, Stoddart SDR, Lilford RJ: A systematic review of tests of empathy in medicine. BMC Med Educ. 2007, 7: 24-10.1186/1472-6920-7-24.

  5. 5.

    Mercer SW, Reynolds WJ: Empathy and quality of care. Br J Gen Pract. 2002, 52 (Suppl): S9-S12.

  6. 6.

    Derksen F, Bensing J, Lagro-Janssen A: Effectiveness of empathy in general practice: a systematic review. Br J Gen Pract. 2013, 63: e76-e84. 10.3399/bjgp13X660814.

  7. 7.

    Bertakis KD, Roter D, Putnam SM: The relationship of physician medical interview style to patient satisfaction. J Fam Pract. 1991, 32: 175-181.

  8. 8.

    Epstein RM, Hadee T, Carroll J, Meldrum SC, Lardner J, Shields CG: “Could this be something serious?” Reassurance, uncertainty, and empathy in response to patients’ expressions of worry. J Gen Intern Med. 2007, 22: 1731-1739. 10.1007/s11606-007-0416-9.

  9. 9.

    Hojat M, Louis DZ, Maxwell K, Markham FW, Wender RC, Gonnella JS: A brief instrument to measure patients’ overall satisfaction with primary care physicians. Fam Med. 2011, 43: 412-417.

  10. 10.

    Kim SS, Kaplowitz S, Johnston MV: The effects of physician empathy on patient satisfaction and compliance. Eval Health Prof. 2004, 27: 237-251. 10.1177/0163278704267037.

  11. 11.

    Pollack KI, Alexander SC, Tulsky JA, Lyna P, Coffman CJ, Dolor RJ, Gulbrandsen P, Ostbye T: Physician empathy and listening: associations with patient satisfaction and autonomy. J Am Board Fam Med. 2011, 24: 665-672. 10.3122/jabfm.2011.06.110025.

  12. 12.

    Zachariae R, Pedersen CG, Jensen AB, Ehrnrooth E, Rossen PB, Von der Maase H: Association of perceived physician communication style with patient satisfaction, distress, cancer-related self-efficacy, and perceived control over the disease. Br J Cancer. 2003, 88: 658-665. 10.1038/sj.bjc.6600798.

  13. 13.

    Stewart MA: What is a successful doctor-patient interview? A study of interactions and outcomes. Soc Sci Med. 1984, 19: 167-175. 10.1016/0277-9536(84)90284-3.

  14. 14.

    Squier RW: A model of empathic understanding and adherence to treatment regimens in practitioner-patient relationships. Soc Sci Med. 1990, 30: 325-339. 10.1016/0277-9536(90)90188-X.

  15. 15.

    Zolnierek KB: Physician communication and patient adherence to treatment: a meta-analysis. Med Care. 2009, 47: 826-834. 10.1097/MLR.0b013e31819a5acc.

  16. 16.

    Attar HS, Chandramani S: Impact of physician empathy on migraine disability and migraineur compliance. Ann Indian Acad Neurol. 2012, 15: S89-S94.

  17. 17.

    Hojat M, Louis DZ, Markham FW, Wender R, Rabinowitz C, Gonnella JS: Physicians' empathy and clinical outcomes for diabetic patients. Acad Med. 2011, 86: 359-364. 10.1097/ACM.0b013e3182086fe1.

  18. 18.

    Lobchuk MM, Bokhari SA: Linkages among empathic behaviors, physical symptoms, and psychological distress in patients with ovarian cancer: a pilot study. Oncol Nurs Forum. 2008, 35: 808-814. 10.1188/08.ONF.808-814.

  19. 19.

    Rakel DP, Hoeft TJ, Barrett BP, Chewning BA, Craig BM, Niu M: Practitioner empathy and the duration of the common cold. Fam Med. 2009, 41: 494-501.

  20. 20.

    Rakel D, Barrett B, Zhang Z, Hoeft T, Chewning B, Marchard L, Scheder J: Perceptions of empathy in the therapeutic encounter: Effects on the common cold. Patient Educ Couns. 2011, 85: 390-397. 10.1016/j.pec.2011.01.009.

  21. 21.

    Thomas MR, Dyrbye LN, Huntington JL, Lawson KL, Novotny PJ, Sloan JA, Shanafelt TD: How do distress and well-being relate to medical student empathy? A multicenter study. J Gen Intern Med. 2007, 22: 177-183. 10.1007/s11606-006-0039-6.

  22. 22.

    DiLalla LF, Hull SK, Dorsey JK: Effect of gender, age, and relevant course work on attitudes toward empathy, patient spirituality, and physician wellness. Teach Learn Med. 2004, 16: 165-170. 10.1207/s15328015tlm1602_8.

  23. 23.

    Shanafelt TD, West C, Zhao X, Novotny P, Kolars J, Habermann T, Sloan J: Relationship between increased personal well-being and enhanced empathy among internal medicine residents. J Gen Intern Med. 2005, 20: 559-564. 10.1007/s11606-005-0102-8.

  24. 24.

    Beckman HB, Markakis KM, Suchman AL, Frankel RM: The doctor-patient relationship and malpractice. Lessons from plaintiff depositions. Arch Intern Med. 1994, 154: 1365-1370. 10.1001/archinte.1994.00420120093010.

  25. 25.

    Levinson W, Roter DL, Mullooly JP, Dull VT, Frankel RM: Physician-patient communication. The relationship with malpractice claims among primary care physicians and surgeons. JAMA. 1997, 277: 553-559. 10.1001/jama.1997.03540310051034.

  26. 26.

    Moore PJ, Adler NE, Robertson PA: Medical malpractice: the effect of doctor-patient relations on medical patient perceptions and malpractice intentions. West J Med. 2000, 173: 244-250. 10.1136/ewjm.173.4.244.

  27. 27.

    Epstein RM, Franks P, Shields CG, Meldrum SC, Miller KN, Campbell TL, Fiscella K: Patient-centered communication and diagnostic testing. Ann Fam Med. 2005, 3: 415-421. 10.1370/afm.348.

  28. 28.

    Pollak KI, Arnold RM, Jeffreys AS, Alexander SC, Olsen MK, Abernethy AP, Sugg Skinner C, Rodriguez KL, Tulsky JA: Oncologist communication about emotion during visits with patients with advanced cancer. J Clin Oncol. 2007, 25: 5748-5752. 10.1200/JCO.2007.12.4180.

  29. 29.

    Easter DW, Beach W: Competent patient care is dependent upon attending to empathic opportunities presented during interview sessions. Curr Surg. 2004, 61: 313-318. 10.1016/j.cursur.2003.12.006.

  30. 30.

    Eide H, Frankel R, Haaversen ACB, Vaupel KA, Graugaard PK, Finset A: Listening for feelings: identifying and coding empathic and potential empathic opportunities in medical dialogues. Patient Educ Couns. 2004, 54: 291-297. 10.1016/j.pec.2003.09.006.

  31. 31.

    Levinson W, Gorawara-Bhat R, Lamb J: A study of patient clues and physician responses in primary care and surgical settings. JAMA. 2000, 284: 1021-1027. 10.1001/jama.284.8.1021.

  32. 32.

    Morse DS, Edwardsen EA, Gordon HS: Missed opportunities for interval empathy in lung cancer communication. Arch Intern Med. 2008, 168: 1853-1858. 10.1001/archinte.168.17.1853.

  33. 33.

    Goore Z, Mangione-Smith R, Elliott MN, McDonald L, Kravitz RL: How much explanation is enough? A study of parent requests for information and physician responses. Ambul Pediatr. 2001, 1: 326-332. 10.1367/1539-4409(2001)001<0326:HMEIEA>2.0.CO;2.

  34. 34.

    Bellini LM, Shea JA: Mood change and empathy decline persist during three years of internal medicine training. Acad Med. 2005, 80: 164-167. 10.1097/00001888-200502000-00013.

  35. 35.

    Chen DC, Lew R, Hershman W, Orlander J: A cross-sectional measurement of medical student empathy. J Gen Intern Med. 2007, 22: 1434-1438. 10.1007/s11606-007-0298-x.

  36. 36.

    Chen DC, Kirshenbaum DS, Yan J, Kirshenbaum E, Aseltine RH: Characterizing changes in student empathy throughout medical school. Med Teach. 2012, 34: 305-311. 10.3109/0142159X.2012.644600.

  37. 37.

    Hojat M, Mangione S, Nasca TJ, Rattner S, Erdmann JB, Gonnella JS, Magee M: An empirical study of decline in empathy in medical school. Med Educ. 2004, 38: 934-941. 10.1111/j.1365-2929.2004.01911.x.

  38. 38.

    Neumann M, Edelhäuser F, Tauschel D, Fischer MR, Wirtz M, Woopen C, Haramati A, Scheffer C: Empathy decline and its reasons: a systematic review of studies with medical students and residents. Acad Med. 2011, 86: 996-1009. 10.1097/ACM.0b013e318221e615.

  39. 39.

    Newton BW, Barber L, Clardy J, Cleveland E, O’Sullivan P: Is there hardening of the heart during medical school?. Acad Med. 2008, 83: 244-249. 10.1097/ACM.0b013e3181637837.

  40. 40.

    Stepien KA, Baernstein A: Educating for empathy: a review. J Gen Intern Med. 2006, 21: 524-530. 10.1111/j.1525-1497.2006.00443.x.

  41. 41.

    Hojat M: Ten approaches for enhancing empathy in health and human services cultures. J Health Hum Serv Adm. 2009, 31: 412-450.

  42. 42.

    Airagnes G, Consoli SM, Morlhon OD, Galliot AM, Lemogne C, Jaury P: Appropriate training based on Balint groups can improve the empathic abilities of medical students: a preliminary study. J Psychosom Res. 2014, 76: 426-429. 10.1016/j.jpsychores.2014.03.005.

  43. 43.

    Bayne HB: Training medical students in empathic communication. JSGW. 2011, 36: 316-329.

  44. 44.

    Bays AM, Engelberg RA, Back AL, Ford DW, Downey L, Shannon SE, Doorenbos AZ, Edlund B, Christianson P, Arnold RW, O’Connor K, Kross EK, Reinke LF, Feemster LC, Fryer-Edwards K, Alexander SC, Tulsky JA, Curtis JR: Interprofessional communication skills training for serious illness: evaluation of a small-group, simulated patient intervention. J Palliat Med. 2014, 17: 159-166. 10.1089/jpm.2013.0318.

  45. 45.

    Bond AR, Mason HF, Lemaster CM, Shaw SE, Mullin CS, Holick EA, Saper RB: Embodied health: the effects of a mind-body course for medical students. Med Educ Online. 2013, 18: 1-8.

  46. 46.

    Bonvicini KA, Perlin MJ, Bylund CL, Carroll G, Rouse RA, Goldstein MG: Impact of communication training on physician expression of empathy in patient encounters. Patient Educ Couns. 2009, 75: 3-10. 10.1016/j.pec.2008.09.007.

  47. 47.

    Bosse HM, Schultz JH, Nickel M, Lutz T, Möltner A, Jünger J, Huwendiek S, Nikendei C: The effect of using standardized patients or peer role play on ratings of undergraduate communication training: a randomized controlled trial. Patient Educ Couns. 2012, 87: 300-306. 10.1016/j.pec.2011.10.007.

  48. 48.

    Bunn W, Terpstra J: Cultivating empathy for the mentally ill using simulated auditory hallucinations. Acad Psychiatry. 2009, 33: 457-460. 10.1176/appi.ap.33.6.457.

  49. 49.

    Cahan MA, Larkin AC, Starr S, Wellman S, Haley HL, Sullivan K, Shah S, Hirsh M, Litwin D, Quirk M: A human factors curriculum for surgical clerkship students. Arch Surg. 2010, 145: 1151-1157. 10.1001/archsurg.2010.252.

  50. 50.

    Cataldo KP, Peeden K, Geesey ME, Dickerson L: Association between balint training and physician empathy and work satisfaction. Fam Med. 2005, 37: 328-331.

  51. 51.

    Chunharas A, Hetrakul P, Boonyobol R, Udomkitti T, Tassanapitikul T, Wattanasirichaigoon D: Medical students themselves as surrogate patients increased satisfaction, confidence, and performance in practicing injection skill. Med Teach. 2013, 35: 308-313. 10.3109/0142159X.2012.746453.

  52. 52.

    Cinar O, AK M, Sutcigil L, Congologlu ED, Canbaz H, Kilic E, Ozmenler KN: Communication skills training for emergency medicine residents. Eur J Emerg Med. 2012, 19: 9-13. 10.1097/MEJ.0b013e328346d56d.

  53. 53.

    Daeppen JB, Fortini C, Bertholet N, Bonvin R, Berney A, Michaud PA, Layat C, Gaume J: Training medical students to conduct motivational interviewing: a randomized controlled trial. Patient Educ Couns. 2012, 87: 313-318. 10.1016/j.pec.2011.12.005.

  54. 54.

    Delvaux N, Merckaert I, Marchal S, Libert Y, Conradt S, Boniver J, Etienne AM, Fontaine O, Janne P, Klastersky J, Melot C, Reynaert C, Scalliet P, Slachmuylder JL, Razavi D: Physicians’ communication with a cancer patient and a relative: a randomized study assessing the efficacy of consolidation workshops. Cancer. 2005, 103: 2397-2411. 10.1002/cncr.21093.

  55. 55.

    Dikici MF, Yaris F, Cubukcu M: Teaching medical students how to break bad news: a Turkish experience. J Cancer Educ. 2009, 24: 246-248. 10.1080/08858190902972814.

  56. 56.

    Dow AW, Leong D, Anderson A, Wenzel RP: Using theater to teach clinical empathy: a pilot study. J Gen Intern Med. 2007, 22: 1114-1118. 10.1007/s11606-007-0224-2.

  57. 57.

    Fallowfield L, Jenkins V, Farewell V, Saul J, Duffy A, Eves R: Efficacy of a Cancer Research UK communication skills training model for oncologists: a randomized controlled trial. Lancet. 2002, 359: 650-656. 10.1016/S0140-6736(02)07810-8.

  58. 58.

    Farnill D, Todisco J, Hayes SC, Bartlett D: Videotaped interviewing of non-English speakers: training for medical students with volunteer clients. Med Educ. 1997, 31: 87-93. 10.1111/j.1365-2923.1997.tb02464.x.

  59. 59.

    Fernández-Olano C, Montoya-Fernández J, Salinas-Sánchez AS: Impact of clinical interview training on the empathy level of medical students and medical residents. Med Teach. 2008, 30: 322-324. 10.1080/01421590701802299.

  60. 60.

    Fine VK, Therrien ME: Empathy in the doctor-patient relationship: skill training for medical students. J Med Educ. 1977, 52: 752-757.

  61. 61.

    Garcia D, Bautista O, Venereo L, Coll O, Vassena R, Vernaeve V: Training in empathic skills improves the patient-physician relationship during the first consultation in a fertility clinic. Fertil Steril. 2013, 99: 1413-1418. 10.1016/j.fertnstert.2012.12.012.

  62. 62.

    Ghetti C, Chang J, Gosman G: Burnout, psychological skills, and empathy: balint training in obstetrics and gynecology residents. J Grad Med Educ. 2009, 1: 231-235.

  63. 63.

    Harlak H, Gemalmaz A, Gurel FS, Dereboy C, Ertekin K: Communication skills training: effects on attitudes toward communication skills and empathic tendency. Educ Health (Abingdon). 2008, 21: 62.

  64. 64.

    Hart CN, Drotar D, Gori A, Lewin L: Enhancing parent-provider communication in ambulatory pediatric practice. Patient Educ Couns. 2006, 63: 38-46. 10.1016/j.pec.2005.08.007.

  65. 65.

    Hojat M, Axelrod D, Spandorfer J, Mangione S: Enhancing and sustaining empathy in medical students. Med Teach. 2013, 35: 996-1001. 10.3109/0142159X.2013.802300.

  66. 66.

    Jenkins V, Fallowfield L: Can communication skills training alter physicians’ beliefs and behavior in clinics?. J Clin Oncol. 2002, 20: 765-769. 10.1200/JCO.20.3.765.

  67. 67.

    Karaoglu N, Seker M: Looking for winds of change with a PBL scenario about communication and empathy. HealthMED. 2011, 5: 515-521.

  68. 68.

    Kramer D, Ber R, Moores M: Increasing empathy among medical students. Med Educ. 1989, 23: 168-173. 10.1111/j.1365-2923.1989.tb00881.x.

  69. 69.

    Krasner MS, Epstein RM, Beckman H, Suchman AL, Chapman B, Mooney CJ, Quill TE: Association of an educational program in mindful communication with burnout, empathy, and attitudes among primary care physicians. JAMA. 2009, 302: 1284-1293. 10.1001/jama.2009.1384.

  70. 70.

    Kushner RF, Zeiss DM, Feinglass JM, Yelen M: An obesity educational intervention for medical students addressing weight bias and communication skills using standardized patients. BMC Med Educ. 2014, 14: 53-10.1186/1472-6920-14-53.

  71. 71.

    Liénard A, Merckaert I, Libert Y, Bragard I, Delvaux N, Etienne AM, Marchal S, Meunier J, Reynaert C, Slachmuylder JL, Razavi D: Is it possible to improve residents breaking bad news skills? A randomized study assessing the efficacy of a communication skills training program. Br J Cancer. 2010, 103: 171-177. 10.1038/sj.bjc.6605749.

  72. 72.

    Liénard A, Merckaert I, Libert Y, Bragard I, Delvaux N, Etienne AM, Marchal S, Meunier J, Reynaert C, Slachmuylder JL, Razavi D: Transfer of communication skills to the workplace during clinical rounds: impact of a program for residents. PLoS One. 2010, 5: e12426-10.1371/journal.pone.0012426.

  73. 73.

    Lim BT, Moriarty H, Huthwaite M: “Being-in-role”: A teaching innovation to enhance empathic communication skills in medical students. Med Teach. 2011, 33: e663-e669. 10.3109/0142159X.2011.611193.

  74. 74.

    Misra-Hebert AD, Isaacson JH, Kohn M, Hull AL, Hojat M, Papp KK, Calabrese L: Improving empathy of physicians through guided reflective writing. Int J Med Educ. 2012, 3: 71-77.

  75. 75.

    Mitchell S, Heyden R, Heyden N, Schroy P, Andrew S, Sadikova E, Wiecha J: A pilot study of motivational interviewing training in a virtual world. J Med Internet Res. 2011, 13: e77-10.2196/jmir.1825.

  76. 76.

    Norfolk T, Birdi K, Patterson F: Developing therapeutic rapport: a training validation study. Qual Prim Care. 2009, 17: 99-106.

  77. 77.

    Ozcan CT, Oflaz F, Bakir B: The effect of a structured empathy course on the students of a medical and a nursing school. Int Nurs Rev. 2012, 59: 532-538. 10.1111/j.1466-7657.2012.01019.x.

  78. 78.

    Pacala JT, Boult C, Bland C, O’Brien J: Aging game improves medical students’ attitudes toward caring for elders. Gerontol Geriatr Educ. 1995, 15: 45-57.

  79. 79.

    Poole AD, Sanson-Fisher RW: Long-term effects of empathy training on the interview skills of medical students. Patient Couns Health Educ. 1980, 2: 125-127. 10.1016/S0738-3991(80)80053-X.

  80. 80.

    Razavi D, Merckaert I, Marchal S, Libert Y, Conradt S, Boniver J, Etienne AM, Fontaine O, Janne P, Klastersky J, Reynaert C, Scalliet P, Slachmuylder JL, Delvaux N: How to optimize physicians’ communication skills in cancer care: results of a randomized study assessing the usefulness of posttraining consolidation workshops. J Clin Oncol. 2003, 21: 3141-3149. 10.1200/JCO.2003.08.031.

  81. 81.

    Riess H, Kelley JM, Bailey R, Konowitz PM, Gray ST: Improving empathy and relational skills in otolaryngology residents: a pilot study. Otolaryngol Head Neck Surg. 2011, 144: 120-122. 10.1177/0194599810390897.

  82. 82.

    Riess H, Kelley JM, Bailey RW, Dunn EJ, Phillips M: Empathy training for resident physicians: a randomized controlled trial of a neuroscience-informed curriculum. J Gen Intern Med. 2012, 27: 1280-1286. 10.1007/s11606-012-2063-z.

  83. 83.

    Rosenthal S, Howard B, Schlussel YR, Herrigel D, Smolarz BG, Gable B, Vasquez J, Grigo H, Kaufman M: Humanism at heart: preserving empathy in third-year medical students. Acad Med. 2011, 86: 350-358. 10.1097/ACM.0b013e318209897f.

  84. 84.

    Roter DL, Hall JA, Kern DE, Barker LR, Cole KA, Roca RP: Improving physicians’ interviewing skills and reducing patients' emotional distress. Arch Intern Med. 1995, 155: 1877-1884. 10.1001/archinte.1995.00430170071009.

  85. 85.

    Roter DL, Larson S, Shinitzky H, Chernoff R, Serwint JR, Adamo G, Wissow L: Use of an innovative video feedback technique to enhance communication skills training. Med Educ. 2004, 38: 145-157. 10.1111/j.1365-2923.2004.01754.x.

  86. 86.

    Sands SA, Stanley P, Charon R: Pediatric narrative oncology: Interprofessional training to promote empathy, build teams, and prevent burnout. J Support Oncol. 2008, 6: 307-312.

  87. 87.

    Sanson-Fisher RW, Poole AD: Training medical students to empathize: an experimental study. Med J Aust. 1978, 1: 473-476.

  88. 88.

    Sanson-Fisher RW, Poole AD: Simulated patients and the assessment of medical students’ interpersonal skills. Med Educ. 1980, 14: 249-253. 10.1111/j.1365-2923.1980.tb02269.x.

  89. 89.

    Schell JO, Green JA, Tulsky JA, Arnold RM: Communication skills training for dialysis decision-making and end-of-life care in nephrology. Clin J Am Soc Nephrol. 2013, 8: 675-680. 10.2215/CJN.05220512.

  90. 90.

    Scholer SJ, Brokish PA, Mukherjee AB, Gigante J: A violence-prevention program helps teach medical students and pediatric residents about childhood aggression. Clin Pediatr (Phila). 2008, 47: 891-900. 10.1177/0009922808319965.

  91. 91.

    Schweller M, Costa FO, Antonio MA, Amaral EM, de Carvalho-Filho MA: The impact of simulated medical consultations on the empathy levels of students at one medical school. Acad Med. 2014, 89: 632-637. 10.1097/ACM.0000000000000175.

  92. 92.

    Shapiro J, Morrison E, Boker J: Teaching empathy to first year medical students: evaluation of an elective literature and medicine course. Educ Health (Abingdon). 2004, 17: 73-84. 10.1080/13576280310001656196.

  93. 93.

    Shapiro J, Rucker L, Boker J, Lie D: Point-of-view writing: A method for increasing medical students’ empathy, identification and expression of emotion, and insight. Educ Health (Abingdon). 2006, 19: 96-105. 10.1080/13576280500534776.

  94. 94.

    Shapiro SL, Schwartz GE, Bonner G: Effects of mindfulness-based stress reduction on medical and premedical students. J Behav Med. 1998, 21: 581-599. 10.1023/A:1018700829825.

  95. 95.

    Shapiro SM, Lancee WJ, Richards-Bentley CM: Evaluation of a communication skills program for first-year medical students at the University of Toronto. BMC Med Educ. 2009, 9: 11-10.1186/1472-6920-9-11.

  96. 96.

    Smith R, Lyles J, Mettler J: A strategy for improving patient satisfaction by the intensive training of residents in psychosocial medicine: a controlled, randomized study. Acad Med. 1995, 70: 729-732. 10.1097/00001888-199508000-00019.

  97. 97.

    Sripada BN, Henry DB, Jobe TH, Winer JA, Schoeny ME, Gibbons RD: A randomized controlled trial of a feedback method for improving empathic accuracy in psychotherapy. Psychol Psychother. 2011, 84: 113-127. 10.1348/147608310X495110.

  98. 98.

    Tiuraniemi J, Läärä R, Kyrö T, Lindeman S: Medical and psychology students’ self-assessed communication skills: A pilot study. Patient Educ Couns. 2011, 83: 152-157. 10.1016/j.pec.2010.05.013.

  99. 99.

    Tulsky JA, Arnold RM, Alexander SC, Olsen MK, Jeffreys AS, Rodriguez KL, Pollack KI: Enhancing communication between oncologists and patients with a computer-based training program: a randomized trial. Ann Intern Med. 2011, 155: 593-601. 10.7326/0003-4819-155-9-201111010-00007.

  100. 100.

    Van Winkle LJ, Fjortoft N, Hojat M: Impact of a workshop about aging on the empathy scores of pharmacy and medical students. Am J Pharm Educ. 2012, 76: 9-10.5688/ajpe7619.

  101. 101.

    Varkey P, Chutka DS, Lesnick TG: The Aging Game: improving medical students’ attitudes toward caring for the elderly. J Am Med Dir Assoc. 2006, 7: 224-229. 10.1016/j.jamda.2005.07.009.

  102. 102.

    Walters P, Tylee A, Fisher J, Goldberg D: Teaching junior doctors to manage patients who somatise: is it possible in an afternoon?. Med Educ. 2007, 41: 995-1001. 10.1111/j.1365-2923.2007.02833.x.

  103. 103.

    Winefield HR, Chur-Hansen A: Evaluating the outcome of communication skill teaching for entry-level medical students: does knowledge of empathy increase?. Med Educ. 2000, 34: 90-94. 10.1046/j.1365-2923.2000.00463.x.

  104. 104.

    Wolf FM, Woolliscrof JO, Calhoun JG, Boxer GJ: A controlled experiment in teaching students to respond to patients’ emotional concerns. J Med Educ. 1987, 62: 25-34.

  105. 105.

    Yang KT, Yang JH: A study of the effect of a visual arts-based program on the scores of Jefferson scale for physician empathy. BMC Med Educ. 2013, 13: 142-10.1186/1472-6920-13-142.

  106. 106.

    Lelorain S, Bredart A, Dolbeault S, Sultan S: A systematic review of the associations between empathy measures and patient outcomes in cancer care. Psychooncology. 2012, 21: 1255-1264. 10.1002/pon.2115.

  107. 107.

    Satterfield JM, Hughes E: Emotion skills training for medical students: a systematic review. Med Educ. 2007, 41: 935-941. 10.1111/j.1365-2923.2007.02835.x.

  108. 108.

    Pedersen R: Empirical research on empathy in medicine-A critical review. Patient Educ Couns. 2009, 76: 307-322. 10.1016/j.pec.2009.06.012.

  109. 109.

    Hojat M, Mangione S, Nasca TJ, Cohen MJM, Gonnella JS, Erdmann JB, Veloski J, Magee M: The Jefferson Scale of Physician Empathy: Development and preliminary psychometric data. Educ Psychol Meas. 2001, 61: 349-365. 10.1177/00131640121971158.

  110. 110.

    Hojat M, Gonnella JS, Nasca TJ, Mangione S, Veloksi JJ, Magee M: The Jefferson Scale of Physician Empathy: Further psychometric data and differences by gender and specialty at item level. Acad Med. 2002, 77: S58-S60. 10.1097/00001888-200210001-00019.

  111. 111.

    Tavakol S, Dennick R, Tavakol M: Psychometric properties and confirmatory factor analysis of the Jefferson Scale of Physician Empathy. BMC Med Educ. 2011, 11: 54-10.1186/1472-6920-11-54.

  112. 112.

    Berg K, Majdan JF, Berg D, Veloski J, Hojat M: A comparison of medical students’ self-reported empathy with simulated patients’ assessments of the students’ empathy. Med Teach. 2011, 33: 388-391. 10.3109/0142159X.2010.530319.

  113. 113.

    Glasner KM, Markham FW, Adler HM, McManus PR, Hojat M: Relationships between scores on the Jefferson Scale of physician empathy, patient perceptions of physician empathy, and humanistic approaches to patient care: a validation study. Med Sci Monit. 2007, 13: CR291-CR294.

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Acknowledgements

We thank Melanie Cedrone, a Biology and Biomedical Graduate Studies Liaison at the Biomedical Library of the University of Pennsylvania, for her advice and collaboration during our initial database search process.

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Affiliations

  1. Ohio University Heritage College of Osteopathic Medicine, Dublin, OH, USA

    • Zak Kelm

  2. Temple University School of Medicine, Philadelphia, PA, USA

    • James Womer

  3. Department of Medical Ethics, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    • James Womer
    • , Jennifer K Walter
    •  & Chris Feudtner

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Correspondence to Chris Feudtner.

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Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

ZK and CF conceived the paper. JW and ZK performed the title and abstract review and extracted the data. JKW, JW, and ZK performed the study design quality assessment and revised the manuscript during the review process. ZK, JW, JKW, and CW participated in the design of the study and interpretation of the data; performed the data analysis; drafted the manuscript; and revised the manuscript for key intellectual content. All authors read and approved the final manuscript.

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Additional file 1: PRISMA 2009 Checklist. Table reporting key PRISMA items by section and page number of the systematic review. (DOC 62 KB)

Additional file 2: Table S1: Intervention studies evaluating quantitative changes in empathy. Table showing the results of all data extraction measures for the 64 qualifying studies. (DOCX 146 KB)

Additional file 3: Table S2: Quality assessment of intervention studies. Description of Dataset: Table showing the quality assessment results of all 64 studies. (DOCX 114 KB)

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Keywords

  • Empathy
  • Compassion emotional intelligence
  • Undergraduate medical education
  • Graduate medical education
  • Continuing medical education
  • Internship and residency

BMC Medical Education

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