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Table 2 Comparison between answers of the students without training (Group 1) and the trained students in infectious diseases (Group 3)

From: Impact of Infectious Diseases training in the perception of antibiotic resistance and rational use of antibiotics among Spanish medical students – a cross-sectional study

 

Group 1%

Group 3%

p

Relevance of the problem

Question 1. Do you think antibiotic resistance is a public health problem?

 Always-Frequently

94.7

99.3

p = 0.02

 Rarely-Never

5.3

0.7

Microbiological cultures

Question 2. Do you think collecting specimens for microbiological cultures before starting empirical antibiotics is mandatory?

 Always-Frequently

68.6

90.3

p < 0.001

 Rarely-Never

31.4

9.7

Empirical antibiotic treatment

Question 3. In a clinically stable patient with documented clinical infection, is it necessary to start empirical antibiotic treatment?

 Always-Frequently

78.3

75.7

p = 0.37

 Rarely-Never

21.7

24.4

Question 4. Before starting empirical antibiotic treatment, should we consider the problem of antibiotic resistance?

 Always-Frequently

96.4

98.4

p = 0.17

 Rarely-Never

3.6

1.6

De-escalation therapy

Question 5. Do you think empirical antibiotic treatment should be adjusted according to microbiological data and clinical evolution?

 Always-Frequently

96.9

97.8

p = 0.63

 Rarely-Never

3.1

2.2

Combination therapy

Question 6. Do you think antibiotic combinations improve clinical results?

 Always-Frequently

93.5

85.3

p = 0.61

 Rarely-Never

6.5

14.7

Prolonged duration

Question 7. Do you think prolonged duration of antibiotic treatment beyond what is recommended by clinical guidelines improves clinical outcomes?

 Always-Frequently

23.2

9.5

p < 0.001

 Rarely-Never

76.8

90.5

Appropriate route

Question 8. Should conversion from parenteral to oral therapy of antibiotics with excellent bioavailability in clinically stable infected be considered?

 Always-Frequently

48.3

84.2

 

 Rarely-Never

51.7

15.8

p < 0.001

Antibiotics for restricted use

Question 9. Do you think use of restricted drugs provides a clinical and microbiological benefit over first-line drugs?

 Always-Frequently

65

45.9

p < 0.001

 Rarely-Never

35

54.1

Antibiotic cost

Question 10. Do you think cost of antibiotic treatment should be considered before its prescription?

 Always-Frequently

67

85.4

p < 0.001

 Rarely-Never

33

14.6

Antibiotic stewardship program

Question 11. Do you know the Antibiotic Stewardship Program?

 Yes

9.3

52.2

p < 0.001

 No

90.7

47.8

Question 12. Do you think the antibiotic Stewardship Program can improve medical training and clinical outcomes in the hospitals in which it is established?

 Always-Frequently

99

99.1

p = 0.97

 Rarely-Never

1

0.9