Table 5 Effects of nationality, respondent sex, sex of relative, generation, and laterality (among second-degree and third-degree relatives) on the familial aggregation of physicians among medical students, separately for first-degree, second-degree and third-degree relatives (includes parents’ siblings-in-law)
Effect | b (SE) | OR [95% confidence interval] |
|---|---|---|
First-degree relatives | ||
 Nationality (German/other vs. Austrian) | 0.23 (0.17) | 1.26 [0.90–1.74] |
 Respondent sex (men vs. women) | −0.13 (0.38) | 0.88 [0.41–1.86] |
 Generation (parents vs. siblings) | 0.80 (0.32)* | 2.23 [1.20–4.15] |
 Sex of relative (men vs. women) | −0.71 (0.45) | 0.49 [0.20–1.19] |
 Respondent sex (men) × generation (parents) | −0.16 (0.45) | 0.85 [0.35–2.08] |
 Respondent sex (men) × sex of relative (men) | 0.37 (0.58) | 1.44 [0.46–4.51] |
 Generation (parents) × sex of relative (men) | 1.75 (0.46)*** | 5.77 [2.32–14.32] |
 Respondent sex (men) × generation (parents) × sex of relative (men) | 0.10 (0.63) | 1.10 [0.32-3.80] |
Second-degree relatives | ||
 Nationality (German/other vs. Austrian) | 0.28 (0.16) | 1.33 [0.97–1.81] |
 Respondent sex (men vs. women) | −0.27 (0.28) | 0.77 [0.44–1.33] |
 Laterality (paternal vs. maternal) | 0.20 (0.26) | 1.22 [0.74–2.02] |
 Generation (grandparents vs. aunts/uncles) | −0.66 (0.26)* | 0.52 [0.31–0.86] |
 Sex of relative (men vs. women) | 0.57 (0.24)* | 1.76 [1.10–2.82] |
 Respondent sex (men) × laterality (paternal) | 0.37 (0.29) | 1.45 [0.83–2.54] |
 Respondent sex (men) × generation (grandparents) | 0.11 (0.22) | 1.11 [0.73–1.70] |
 Respondent sex (men) × sex of relative (men) | −0.01 (0.25) | 0.99 [0.60–1.61] |
 Laterality (paternal) × generation (grandparents) | −0.09 (0.21) | 0.91 [0.60–1.38] |
 Laterality (paternal) × sex of relative (men) | −0.34 (0.22) | 0.71 [0.46–1.10] |
 Generation (grandparents) × sex of relative (men) | 0.70 (0.23)** | 2.02 [1.29–3.16] |
Third-degree relatives and parents’ siblings-in-law | ||
 Nationality (German/other vs. Austrian) | 0.29 (0.18) | 1.33 [0.93–1.91] |
 Respondent sex (men vs. women) | −0.64 (0.27)* | 0.53 [0.31–0.90] |
 Laterality (paternal vs. maternal) | −0.07 (0.24) | 0.93 [0.58–1.50] |
 Generation (parents’ siblings-in-law vs. cousin) | −0.86 (0.23)*** | 0.42 [0.27–0.67] |
 Sex of relative (men vs. women) | −0.77 (0.22)** | 0.46 [0.30–0.72] |
 Respondent sex (men) × laterality (paternal) | 0.11 (0.30) | 1.11 [0.62–2.01] |
 Respondent sex (men) × generation (parents’ sibling-in-law) | 0.38 (0.26) | 1.45 [0.87–2.43] |
 Respondent sex (men) × sex of relative (men) | 0.37 (0.24) | 1.45 [0.92–2.30] |
 Laterality (paternal) × generation (parents’ siblings-in-law) | −0.10 (0.25) | 0.91 [0.55–1.49] |
 Laterality (paternal) × sex of relative (men) | 0.40 (0.24) | 1.50 [0.93–2.40] |
 Generation (parents’ siblings-in-law) × sex of relative (men) | 0.65 (0.26)* | 1.91 [1.15–3.17] |