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Table 1 Main characteristics of the articles included in the reviewphase

From: Developing and validating of the Clinical Uncertainty Measurement Questionnaire (CUMQ) among practicing physicians and clinical residents in Iran

Code

Title

Author

Year

Derived items to help finding uncertainty determinants

1

Twelve tips for thriving in the face of clinical uncertainty

Gheihman et al. [20]

2020

-Everyone should know their reaction in cases of uncertainty

- One must identify the type and source of uncertainty

-Identify cognitive biases

- Planning for uncertainty: Use a secure network and track

- Do not worry about loneliness, rely on your colleagues

- Culture building: a pattern of accepting the inherent uncertainty of clinical medicine

-Promote curiosity among students more than certainty

-Be clear about the level of uncertainty

-Include uncertainty explicitly in medical education courses

-Talk to patients about uncertainty in public

-Use patients as allies in joint decision making

2

Decision-making under uncertainty in environmental health policy: newapproaches

Reis and Spencer [21]

2019

- Accepting the uncertainty of science

- Teaching the principle of scientific uncertainty to all stakeholders and policy makers

3

Decision-Making under Uncertain Conditions: The Internist, as a Director of the Diagnostic/Therapeutic Pathway in Grey Zones

Tirotta and Durante [18]

2018

-Predict frequently asked questions about the patient's problem (problem, intervention, exposure, outcome)

- Determine the best available evidence and make a decision

- Perform critical evaluation and information transfer

- Patient and specialist consultation

- Another doctor's opinion

-Referral to another medical center with a higher number of similar cases admitted to specific cases

-Consider a collection of patients, physicians, evidence, Gray Literature, socioeconomic context, and expertise in related fields

4

Uncertainty of Physicians and Patients inMedical DecisionMaking

Dhawale et al. [22]

2017

-Accepting and understanding uncertainty

-Effective communication between doctor and patient

- Predict the risk of disease consequences based on its recurrence in the past

5

Uncertainty and objectivity in clinical decision making: a clinicalcase in emergency medicine

Engebretsen et al. [23]

2016

- Analysis of emergency cases

- Active questions

6

The Diagnosis, Prognosis, and Treatment of Medical Uncertainty

Wray and Loo [12]

2015

- Teaching students the inherent medical uncertainty

- Supervising schools to change the prevailing view of uncertainty

- Share decisions with the patient

- Using experienced doctors and consulting with them

- Refer to evidence-based sources

- Refer to the guidelines

Opportunity to write with feedback and ways such as role modeling to express uncertainty

7

Recognizing and Responding to Uncertainty: A Grounded Theory Uncertainty

Cranley et al. [24]

2012

- Imagine the situation for yourself

- Consult with other colleagues

- Search for evidence and sources

- Training programs to increase the ability to deal with uncertainty

8

Risk, Uncertainty and Indeterminacy in Clinical Decisions

Strand et al. [25]

2010

Risk, consequences and effectiveness of different treatments

- Severe uncertainty about the patient's condition and ignorance of his characteristics

- Unawareness of the consequences of the decision and the side effects of the treatment of choice

- Uncertainty of clinical problem

9

Resident uncertainty in clinical decision making and impact on patient care: a qualitative study

Farnan et al. [13]

2008

-Consult with people around you

- Consult with experienced doctors