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Table 1 Program Details

From: Formal evidence-based medicine instruction in Turkish undergraduate medical education: an initial evaluation

Week

Outline

Objectives

Content

Educational Method

  

By the end of the session students will be able to:

  

1.

▪ Pre-test

▪ Introduction to EBM practice

▪ Formulating focused clinical questions using the PICO formula

▪ Explain the concept of EBM

▪ List the components of the PICO formula

▪ Understand types of the PICO question

▪ Formulate a focused clinical question

▪ Value ​​using the most reliable scientific evidence as well as professional experience and patient’s values together on clinical decision

▪ Students were informed about the course

▪ Pre-test was applied before the main training started

▪ An interactive lecture was given about the concept of EBM and the creation of clinical questions using the PICO format

▪ A homework assignment was given at the end of the lecture

▪ Interactive classroom lecture

▪ Homework assignment

2

PubMed Class

▪ Explore different databases and understand their strengths and weaknesses

▪ Create search strategies by using Boolean operators (AND, OR, NOT)

▪ Perform MeSH database search

▪ Know how to find MeSH terms

▪ Use PubMed tags and filters

▪ The workshop was held in a computer lab where each student could work with an individual computer

▪ The training included the use of Boolean operators, MeSH database search, creating search strategies, using search filters, creating an NCBI account and setting e-mail alerts for saved searches

Workshop

3

Designing Scientific Research

▪ Name different types of scientific research designs

▪ Explain levels of evidence by using hierarchy of evidence pyramid

▪ Explain the concept of randomization

▪ Explain the importance of allocation concealment

▪ Understand the concept of blinding

The course content included introducing different study designs, randomized controlled trials, cohort studies, diagnostic and prognostic studies, bias in scientific research, prevention of bias, and the EBM pyramid.

Interactive classroom lecture

4

Biostatistics

▪ List the concepts used in the evaluation of statistical significance (such as p value, confidence interval, type I and type II errors)

▪ Give an example of confidence interval expressing statistical significance

▪ Calculate following measures given clinical scenarios

o Sensitivity

o Specificity

o Positive predictive value

o Negative predictive value

o Probability ratio values

o Absolute risk reduction

o Relative risk reduction

o Numbers Needed to Treat (NNT)

Statistic class was designed to understand the biostatistical approaches in scientific articles. Therefore, especially risk calculations, measures of diagnostic accuracy, Type I and II errors, confidence intervals, and p value were discussed.

Interactive classroom lecture

5

▪ Critical appraisal of scientific articles

▪ Post-test

▪ Students’ satisfaction survey

▪ Understand the concepts of internal and external validity of scientific research

▪ Explain the concept of bias

▪ List the most common types of bias

▪ Use the critical appraisal tools

▪ During the last week, the critical appraisal of scientific articles was discussed interactively

▪ The main theme of the training was the evaluation of the validity and reliability of scientific research using checklists

▪ After the completion of the fifth week of education, the post-test and the student satisfaction survey were applied

Critical appraisal workshop