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Table 6 Diagnostic outcomes by NT-proBNP (125 ng/L cut-off)

From: Hand-held cardiac ultrasound examinations performed in primary care patients by nonexperts to identify reduced ejection fraction

Diagnostic outcomeNT-proBNP > 125 ng/L (n = 94), n (%)NT-proBNP ≤125 ng/L (n = 64), n (%)P value for difference
HFpEF50 (53.2%)NANA
HFmrEF11 (11.7%)NANA
HFrEF7 (7.4%)00.042
Heart-failure criteria not fulfilled26 (27.7%)64 (100%)< 0.001
  1. NT-proBNP N-terminal pro-B type natriuretic peptide, serum level in ng/L. HFpEF was defined as LVEF ≥50%, NT-proBNP > 125 ng/L, and at least one additional criterion; a) signs of relevant structural heart disease (LVH and/or LAE) or b) diastolic dysfunction. HFmrEF was defined as LVEF 40 to 49%, NT-proBNP > 125 ng/L, and at least one additional criterion; a) or b). HFrEF was defined as LVEF <40%. LVH Left ventricular hypertrophy, LAE Left atrial enlargement. Patients were treated in a primary care setting and examined by comprehensive cardiac ultrasound (n = 158)