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Table 1 The input variables used to model the various pathophysiological processes with the LPM

From: Computer model for the cardiovascular system: development of an e-learning tool for teaching of medical students

Inputs

Pathological Process

LVEmax

R

C

Volume

T

mmhg/ml

mmhg.s/min

ml/mmhg

(ml)

(s)

Normal

2.5

0.094

1.7

5700

1

Hypertension

Stage 1

2.5

1.194

1.26

5700

1

Stage 2

2.7

1.374

1.16

5700

1

Accelerated

2.7

1.614

1.16

5700

1

Heart Failure

Mild

2

1.094

1.7

5700

1

Moderate

1.4

1.094

1.65

5700

0.857

Severe

0.8

1.194

1.55

5700

0.75

Haemorrhage

Stage I

2.8

0.994

1.7

5200

0.6

Stage II

3.2

1.034

1.7

4500

0.5

Stage III

3

1.034

1.7

3700

0.429

Stage IV

3

1.018

1.7

2850

0.375

  1. C Total arterial compliance, LVEmax Maximal left ventricular elastance, R systemic vascular resistance, T duration of each heartbeat (i.e. 60/heart rate), Volume circulating blood volume
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