Table 1 List of podcast episodes and learning objectives

 1.

Vitamin A

3′ 00ʼ

a) Name the active forms of vitamin A and their physiological role

b) List the dietary sources of vitamin A

c) List the functions of vitamin A

d) List the clinical features of vitamin A deficiency

 2.

Vitamin D: metabolism and functions

2′ 55ʼ

a) Name the active form of vitamin D

b) Define the role of skin, liver and kidneys in the metabolism of vitamin D

c) List the functions of vitamin D

 3.

Regulation of vitamin D metabolism and its deficiency

2′ 30ʼ

a) List the factors regulating vitamin D metabolism

b) List the causes for vitamin D deficiency

c) List the clinical manifestations of vitamin D deficiency

 4.

Vitamin K and Vitamin E

2′ 53ʼ

a) Name the active forms of vitamin K and E

b) Explain the biological roles of vitamin K and vitamin E

c) List the proteins activated by vitamin K

d) Explain the effect of warfarin on vitamin K metabolism

e) List the clinical manifestations of vitamin K deficiency

 5.

Heme biosynthesis

2′ 57ʼ

a) List the precursors for heme biosynthesis

b) Name the major tissues involved in heme biosynthesis

c) Name the rate limiting enzyme for heme biosynthesis

d) Outline the biosynthesis of heme

 6.

Porphyrias

2′ 59ʼ

a) Classify porphyrias

b) List the common clinical features of porphyrias

c) Explain the basis behind clinical presentation of porphyrias

 7.

Disorders of hemoglobin – Sickle cell disease

2′ 56ʼ

a) Explain the molecular defect in sickle cell disease

b) Explain the biochemical basis of symptoms in sickle cell disease

 8.

Disorders of hemoglobin - Thalassemia

2′ 52ʼ

a) Explain the molecular defect in thalassemia

b) Explain the biochemical basis of symptoms in thalassemia