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Table 10 Cardiovascular nurses’ knowledge on warfarin-drug interactions

From: Education and practice gaps on atrial fibrillation and anticoagulation: a survey of cardiovascular nurses

Question n (%) n (%) n (%) n (%)  
  Enhance Inhibit No effect Don’t know Rating Count
How to these anti-inflammatory agents affect oral warfarin anticoagulant therapy?
 • Aspirin  • Ibuprofen  • Topical salicylates 34 (69) 23 (48) 11 (23) 2 (4) 8 (17) 3 (6) 9 (18) 9 (18) 11 (23) 4 (8) 8 (17) 23 (48) 49 48 48
How do these cardiac agents affect oral warfarin anticoagulant therapy?
 • Propanolol  • Cholestyramine  • Atenolol 7 (15) 0 (0) 5 (11) 2 (4) 10 (21) 1 (2) 15 (32) 6 (13) 20 (44) 23 (49) 32 (67) 20 (44) 47 48 46
How do these gastrointestinal agents affect warfarin anticoagulant therapy?
 • Antiacids  • Cimetidine  • Metamucol  • Sucralfate 0 (0) 4 (9) 1 (2) 0 (0) 23 (49) 11 (24) 10 (22) 10 (22) 7 (15) 4 (9) 5 (11) 5 (11) 17 (36) 27 (59) 30 (65) 30 (67) 47 46 46 45
How do these vitamin supplement (s) affect oral anticoagulant therapy?
 • Multivitamin  • Multivitamin and minerals  • Antioxidant formula  • 1200 IU vitamin E  • 1000 mg vitamin C 2 (4) 2 (4) 7 (16) 18 (39) 4 (9) 9 (20) 9 (20) 3 (7) 5 (11) 3 (7) 15 (33) 15 (33) 9 (21) 3 (7) 12 (27) 19 (42) 19 (42) 25 (57) 20 (44) 26 (58) 45 45 44 46 45
Most antibiotics affect warfarin therapy by the process of:
 • Potentiation  • Inhibition  • Both  • Neither(other process)   7 (23) 5 (17) 6 (19) 1 (4) 0 (0) 0 (0) 1 (4) 2 (8) 24 (78) 25 (84) 25 (78) 23 (89) 31 30 32 26
  1. Correct answers are shown in bold