Table 10 Cardiovascular nurses’ knowledge on warfarin-drug interactions
Question | n (%) | n (%) | n (%) | n (%) | |
|---|---|---|---|---|---|
Enhance | Inhibit | No effect | Don’t know | Rating Count | |
How to these anti-inflammatory agents affect oral warfarin anticoagulant therapy? | |||||
• Aspirin • Ibuprofen • Topical salicylates | 34 (69) 23 (48) 11 (23) | 2 (4) 8 (17) 3 (6) | 9 (18) 9 (18) 11 (23) | 4 (8) 8 (17) 23 (48) | 49 48 48 |
How do these cardiac agents affect oral warfarin anticoagulant therapy? | |||||
• Propanolol • Cholestyramine • Atenolol | 7 (15) 0 (0) 5 (11) | 2 (4) 10 (21) 1 (2) | 15 (32) 6 (13) 20 (44) | 23 (49) 32 (67) 20 (44) | 47 48 46 |
How do these gastrointestinal agents affect warfarin anticoagulant therapy? | |||||
• Antiacids • Cimetidine • Metamucol • Sucralfate | 0 (0) 4 (9) 1 (2) 0 (0) | 23 (49) 11 (24) 10 (22) 10 (22) | 7 (15) 4 (9) 5 (11) 5 (11) | 17 (36) 27 (59) 30 (65) 30 (67) | 47 46 46 45 |
How do these vitamin supplement (s) affect oral anticoagulant therapy? | |||||
• Multivitamin • Multivitamin and minerals • Antioxidant formula • 1200 IU vitamin E • 1000 mg vitamin C | 2 (4) 2 (4) 7 (16) 18 (39) 4 (9) | 9 (20) 9 (20) 3 (7) 5 (11) 3 (7) | 15 (33) 15 (33) 9 (21) 3 (7) 12 (27) | 19 (42) 19 (42) 25 (57) 20 (44) 26 (58) | 45 45 44 46 45 |
Most antibiotics affect warfarin therapy by the process of: | |||||
• Potentiation • Inhibition • Both • Neither(other process) | 7 (23) 5 (17) 6 (19) 1 (4) | 0 (0) 0 (0) 1 (4) 2 (8) | 24 (78) 25 (84) 25 (78) 23 (89) | 31 30 32 26 | |