Figure 3
Serum/plasma concentration-time Profiles. Serum/plasma concentration-time course of gentamicin after intermittent intravenous infusion in a patient after intravenous infusion of 80 mg of the drug over 30 min every 8 h, demonstrating the manipulation of peak or trough time (A) and calculation of sampling time for peak (Tpeak) and trough (Ttrough) within the interval (B). Solid triangles: peak and trough after the first dose; solid circles: peak and trough at steady state; dotted open circles: transposed peak or trough at steady state.